The online wellness program is an online nutritional, dietary, herbal, nutraceutical counseling program. The program consists of two components that can be ordered separately or together.
Part One is accomplished by filling out the Metabolic Assessment Form. This questionnaire of 188 questions inquires’ into and evaluates your subjective experience of your health symptoms in a visual analogue scale of 1-4. This measurement reflects your symptoms in terms of 5 major metabolic systems of western medicine including; upper and lower gastro intestinal function and permeability, glucose management, liver and gallbladder functions, endocrine function, immune function. The cost of the Metabolic Assessment form profile is 85$ and includes a report of your systems diagnosis and dietary and nutritional recommendations.
There is also the option to engage in the Neurotransmitter Assessment Form. This may be done in addition to Metabolic Assessment Form, but is not offered as a stand-alone assessment. This form of 94 questions, measures your subjective sense of your brain neurochemistry. It evaluates your brain function in terms of 9 areas of western neurological functioning. The cost of the Neurotransmitter profile is an additional 85$ and includes a report of your systems diagnosis and dietary and nutritional recommendations.
Part Two of the online program consists of blood chemistry testing and functional blood chemistry evaluation. The blood chemistry evaluation is not offered separately. After you enroll in the metabolic assessment program, you will have the option to enroll in the Functional Blood Chemistry evaluation program. See below for brief descritpion of functional evaluation, or see Functional Blood chemsity evaluations under the services tab. You may then send in a chemistry results panel rom the last year to be functionally evaluated, or have new blood chemistry testing performed. When you enroll in the evaluation program, you will be notified of the recommended testing based on your metabolic assessment results. This notification will include pricing, instructions and rationale for the testing. Depending on the testing you agree to, your blood will be processed at a lab near you, or sent to another lab for processing. This will all be arranged over the internet. You will only need to go to a local blood draw office or service. If you would like to send in results you will be notified of where to send them.
Most people will see a change in their symptoms within the first week after beginning the program.
Depending on the severity and chronicity of your symptoms, your results will vary. I recommend you stay on the program for two months before making any evaluations or opinions about the efficacy of the program. After two months you may sign up for another Metabolic Assessment Profile. We can then dis youcuss changes in your protocol and other issues such as beginning to reduce medications. I recommend you undertake this program, and any changes in your medications always be done with your Primary Care Physicians Approval. You should always follow the advice of your Primary Care Physician in conjunction with this program. After two months you may also do some follow up testing.
Below is a list of available testing and pricing. The cost of the functional evaluation is an additional 110$ and includes a report and nutritional and dietary recommendations. If you have blood chemistry from within the last year and would like to have a functional evaluation of the results, the cost is 110$ After you pay for the evaluation to enroll in the program you will be notified where to send your test results.
Functional Blood Chemistry Models differ significantly from the commonly used Pathological Models in several significant ways. Functional models view the body as complex integrated systems, and the emphasis is on maintaining normal physiology. Pathological models are very specialized, localized and the emphasis is on identifying disease change. Functional Models integrates data from many different systems and resources of information, and seeks to address the underlying metabolic conditions. Pathological models are based on reducing specific symptoms or markers, without regard for the system as a whole. Pathological chemistry ranges are based on a bell curve which results in 95% of the population falling within normal range. Which is one reason why so many people claim they do not feel well, and their doctors tell them they are? Another reason is the specialized identification of isolated chemistries does not yield the ability to understand and treat relational problems within the greater context of the human organism. The associated treatment strategies suffer from the same problems of isolated chemical reactions aimed at manipulating a particular chemical outcome that does not take into account the rest of the biological terrain which sometimes results in severe, unwanted and unwarranted side effects.
Below is a list of available testing and pricing.
Fat Soluble Vitamins Testing
Measuring circulating levels of fat-soluble vitamins (FSVs) provides a good indication of their status throughout the body. The primary fat-soluble vitamins are involved in a vast array of protective and regulatory functions, and the thoroughly intertwined and complementary actions among some fat-soluble vitamins is impressive with respect to optimization of health and disease prevention. Although overt deficiencies are rare, marginal status of specific FSVs may be affected by poor diet, inappropriate supplementation, smoking, excessive alcohol consumption, malabsorption and increased demand associated with chronic conditions such as cardiovascular disease or diabetes. Soluble Vitamins Profile assesses circulating levels of vitamins D, D2 and D3, as well as beta carotene, CoQ10, vitamin A (retinol), vitamin E (tocopherol alpha and gamma) and vitamin K. All FSVs have vital independent physiological functions, but there are also important interactive functions to consider. For example, addressing vitamin D status without attention to vitamins K and A may be consequential in the long run regarding bone health and undesirable calcium deposition. Beta carotene is the primary plant source of vitamin A, and its conversion to vitamin A varies significantly among individuals, particularly those with low thyroid function, as well as a significant percentage of the female population. Vitamin E and CoQ10 are the primary antioxidants among FSVs and they protect against oxidation of polyunsaturated fatty acids in cell membranes and circulating lipoproteins (oxidized LDL is an independent risk factor for cardiovascular disease). Very high levels of vitamin E may prolong clotting time, which is particularly significant with poor vitamin K status that may impair with the normal coagulation cascade.
Vitamin D profile Testing
25-Hydroxyvitamin D, known for its role in bone health and calcium absorption, also appears to affect immune function, neurodegenerative and cardiovascular diseases, and other conditions. Vitamin D occurs in two forms—D3 is obtained from animal diet sources and through sun exposure, and D2 is obtained through vegetable diet sources. Both forms of the vitamin are used to fortify various foods and in supplements. LC/ MS method to measure Vitamin D2, D3, and total Vitamin D. Vitamin D status is also available via a blood spot profile.
Urine Halides Testing (Iodine, Bromine and Fluoride)
Providing comprehensive assessment of iodine sufficiency and antagonistic halides in a single test, the Urine Halides test assesses iodine as well as exposure to and retention of bromide and fluoride. Iodine is an essential element required for normal function of the thyroid gland and immune system, and the integrity of breast tissue. Bromide and fluoride are non-essential, antagonistic halides that can disrupt iodine homeostasis and function. The test can be performed using conventional random or 24-hour urine collection or after administration of a loading dose of iodide/iodine. Iodine and bromine are measured by ICP-MS, as is used by the CDC.
Iodine, Pre and Post Load Testing
Specific tissues in the body require adequate iodine and the reduced form of the element, iodide, for normal metabolism and optimal health. Adequate iodide uptake and organification of iodine by the thyroid gland is required for the production, storage and release of thyroid hormones. Triiodothyronine (T3) regulates metabolism in several tissues by affecting energy production and neuronal and sexual development. Iodine insufficiency is associated with subclinical thyroid deficiency, weight gain, loss of energy, goiter and impaired mental function. This test is useful for ■ Fatigue ■ Immune response ■ Thyroid function ■ Estrogen metabolism
Plasma Methylation Profile Testing
Normal metabolism of methionine is critical for cellular trans methylation of DNA, proteins and neurotransmitters. Aberrant methionine metabolism can occur in anyone—at any age—and can be associated with a variety of conditions, including cardiovascular disease and cancer. The Plasma Methylation Profile provides a functional assessment of the phenotypic expression of common SNPs (MTHFR, MS, CBS) by evaluating the plasma levels of methionine, cysteine, SAM, SAH, homocysteine and cystathionine, and provides the key methylation index, a ratio of SAM to SAH. The results can be used to determine appropriate nutritional support to normalize methionine metabolism.
Folate Metabolism Profile Testing
This test measures the levels of the primary forms of folate (B-9) in plasma, and can be used to assess folate status and disorders in essential folate metabolism. Assessment of plasma folate species provides clinical insight into aberrant folate metabolism that can significantly affect crucial methylation processes, DNA/RNA metabolism and neurotransmitter metabolism. This plasma Folate Metabolism Profile reports the levels of THF, UMFA, folinic acid and 5-MTHF, and can be used to monitor clinical intervention. It can be run as a single test, or as a basal and one-hour post-folate supplement challenge. It can also be a useful add-on to the functional Plasma Methylation Profile. This test is useful for ■ Prenatal care ■ Folate receptor autoantibodies ■ Nutritional deficiencies ■ Elevated homocysteine ■ Cardiovascular disease ■ Neurotransmitter imbalances ■ Autism ■ Cancer/chemotherapy ■ Detoxification impairment ■ General health and longevity ■ Genetic disorders ■ Assessing functional folate metabolism in variants of MTHFR and COMT ■ Assessing therapeutic interventions of enzymatic deficiencies of methylation ■ Neurodegenerative diseases ■ Psychiatric disorders ■ Behavioral disorders
Urine analysis of Amino Acid Profile Testing
Many people have hidden amino acid (AA) impairments that go undiagnosed. Rather than being associated with specific symptoms, they may be related or increase susceptibility to a degenerative disease. Because this test provides a wealth of valuable information, a complete AA analysis is recommended any time a thorough nutritional and metabolic workup is called for. Plasma is traditionally used to assess the status of essential AA, while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies. AA analysis aids in ■ Dietary protein adequacy and AA balance ■ Gastrointestinal dysfunctions ■ Forms of protein intolerance ■ Vitamin and mineral deficiencies ■ Renal and hepatic dysfunction ■ Psychiatric abnormalities ■ Susceptibility to inflammatory response and oxidative stress ■ Reduced detoxification capacity ■ And many other inherent and acquired disorders in AA metabolism
Comprehensive Metabolic Panel, 220$, this price includes the testing listed for all the following sections together. Except the immunological and other specialty testing listed at the end.
Can also be ordered in smaller bundles listed in the separate sections.
CBC WITH DIFFERENTIAL AND PLATELETS; 18.90$ hb, hct, mcv, mchc, rdw,
WBC, lymphocytes absolute, neutrophils absolute, monocytes absolute, basophils absolute, eosinophils absolute,
Lymphocytes%, neutrophils%, monocytes%, basophils%, eosinophils%
CHEM ADVANTAGE; not available separately
Glucose, Uric acid, bun, creatinine, Bun/creatinine, eGfr,
Sodium, potassium, chloride, calcium, Co2. Phosphorus,
Total protein, Albumin, Globulin, A/G ratio,
Alkaline phosphatase, LDH, AST/SGOT, ALT/SGPT, GGT,
Iron, TIBC, UIBC,
LDH,HDL, Total Cholesterol, Triglycerides, Chol/HDL ratio,
THYROID ADVANTAGE; 98.80$
TSH, T4, T3, T3Uptake, Free Thyroxine index, (FTI)
TPO and Anti-thyroglobulin Antibody,
Free T4,Free T3, reverseT3,
Vitamin D-flam 74.00$
25-OH Vitamin D, Homocysteine, CRPhs, ( high sensitivity)
Additional biomarkers included in Comprehensive Metabolic Panel
Ferritin, Magnesium, Hemoglobin A1C, Fibrinogen, Iron Saturation,
Urinalysis; 8.95$, included in Comprehensive Metabolic Panel,
Color, appearance, specific gravity, PH, Protein, glucose, ketones, nitrate, bilirubin, urobilinogen, occult blood, leukocyte esterase, microscopic analysis of urine sediment.
Iron Advantage 31.90$ included in Complete metabolic panel; Iron TBIC, Iron Saturation, Reticulocyte count,
Taken together these tests are a very complete blood and urinalysis. Other tests and pricing available upon request.
Immune testing is performed Cyrex labs. See their patient portal at www.joincyrex.com for a complete list of their tests and bundles. These are panels for a variety of immune issues listed on their website. Commonly ordered is their food sensitivity panel. They can test for immunological reactions with any tissue in the body. They are the premier immune testing lab, worldwide. Their director, Dr. Vojdani is known for his innovative testing methods that are used in many labs worldwide. Bewlow is a list of available testing.
Array 2 - Intestinal Antigenic Permeability Screen
Array 3X - Wheat/Gluten Proteome Reactivity & Autoimmunity
Array 4 - Gluten-Associated Cross-Reactive Foods and Foods Sensitivity
Array 5 - Multiple Autoimmune Reactivity Screen
Array 6 - Diabetes Autoimmune Reactivity Screen
Array 7 - Neurological Autoimmune Reactivity Screen
Array 7X - Neurological Autoimmune Reactivity Screen - Expanded
Array 8 - Joint Autoimmune Reactivity Screen
Array 10 - Multiple Food Immune Reactivity Screen
Array 10-90 - Multiple Food Immune Reactivity Screen
Array 11 - Chemical Immune Reactivity Screen
Array 12 - Pathogen-Associated Immune Reactivity Screen
Array 14 - Mucosal Immune Reactivity Screen
Array 20 - Blood Brain Barrier Permeability
Array 22 - Irritable Bowel/SIBO Screen
Pathogen Testing is performed by Immunosciences lab, www.immunoscienceslab.com This is another of Dr. Vojdanis’ labs. It is the premier lab for testing for pathogens such as Lyme, STD’s, Epstein Barr, CMV and more. Please see their website for their tests and bundles.
Stool Testing is also available.
Pancreatic Elastase-1 is a marker of exocrine pancreatic function.
Products of Protein Breakdown are markers of undigested protein reaching the colon.
Fecal Fat is a marker of fat breakdown and absorption.
Calprotectin is a marker of neutrophil-driven inflammation. Produced in abundance at sites of inflammation, this biomarker has been proven clinically useful in differentiating between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).3,4
Eosinophil Protein X is a marker of eosinophil-driven inflammation and allergic response.
Fecal Secretory IgA is a marker of gut secretory immunity and barrier function.
Metabolic indicators, including short-chain fatty acids and beta-glucuronidase, demonstrate specific and vital metabolic functions performed by the microbiota.
Commensal Bacteria demonstrate the composition and relative abundance of gut organisms.
More than 95% of commensal gut organisms are anaerobic and are difficult to recover by traditional (aerobic) culture techniques.
GI Effects assesses a set of 24 genera/species that map to 7 major phyla.
Bacterial and mycology cultures demonstrate the presence of specific beneficial and pathological organisms.
Bacterial and mycology sensitivities are provided for pathogenic or potentially pathogenic organisms that have been cultured. The report includes effective prescriptive and natural agents.
Parasitology includes comprehensive testing for all parasites on every parasitology exam ordered.
GI Effects provides microscopic fecal specimen examination for ova and parasites (O&P), the gold standard of diagnosis for many parasites.
6 Polymerase chain reaction (PCR) targets detect common protozoan parasites including Blastocystis spp. with reflex subtyping 1-9, Cryptosporidium spp., Cyclospora cayetanensis, Dientamoeba fragilis, Entamoeba histolytica, and Giardia. PCR for organisms is emerging as a highly sensitive method for infectious organism detection.
Selection of a one-day or three-day sample collection is based on the clinician's clinical index of suspicion for parasitic infection. If there is no/low suspicion, a one-day sample will likely be adequate. For high suspicion, a three-day sample collection is optimal.
Additional Biomarkers Available:
Macro Exam for Worms
Zonulin Family Peptide
KOH Preparation for Yeast
I will evaluate you for any suspected need for specialty testing.
Depending on the severity and chronicity of the problem, you may experience shorter or longer lengths of time to see significant results and changes in blood chemistry markers. Generally a felt change in symptoms occurs before changes in blood chemistry. I will try you an estimate of what you can expect.